This is by no means exhaustive, but here are some artifacts you may encounter. These artifacts are unique, in that there is only one or a limited number of them in the world.
Demon Lords often times have artifacts associated with them.
The Chipped Bell is an ancient hand bell that summons a ghost to assist the one who rings it.
The Veil of Umbrarum allows the wearer to take the identity of any person he or she pleases, and will take on the appearance and voice of that person. However, it is possible for people to take notice of a difference in behavior.
The Solar Axe is an unbreakable magical axe imbued with the power of Solum. In line with Solum's preferences, the axe has nothing special about it other than being a very powerful weapon.
The Oak Trumpet is a speaking-trumpet that allows the speaker to communicate with all animals.
The wearer of the Gloves of Pyromaniac becomes able to cast massive infernos at will to destroy their enemies.
The Skull Necklace is imbued with necrosmithic power.
The Staff of Energiarum is a bizarre magical staff with an unpredictable effect on the target. The effect can be very damaging or very empowering, depending on the whim of the staff.
The Dreadarmor is a coat of pitch black plate armor. Anybody who sees the wearer of the Dreadarmor become terrified of the intimidating armor and will try to run away.
The Doomstaff will summon a Doomstruck to aid the caster.
The Codex Gigas is a book that magically imprints its contents onto the reader, containing secret and powerful knowledge. However the book is unpredictable in what knowledge it grants to the reader.
The Thief's Ring makes the wearer completely invisible.
The Skeleton Key can open any door.
The Blue Edge is a magical sword that deals icy damage.
Sunspark is a sword associated with the Church of Gora, imbued with powerful Anti-Demonic energy.
Stormfire is a masterfully built revolver, crafted by legendary Orcish smith Yagrak kar-Lazdar.